One way of looking at intangibles is, they are business assets that cannot be physically touched.
The biggest question to answer when it comes to operating in other states is to determine if you’re “doing business” in another state. In general, if you’re “on the ground” in another state providing a service or selling your product, you probably have a business presence in that state.
There are tax considerations and non-tax considerations when you have employees. You should think about both before making the leap and hiring employees.